Publications

(Thesis). Ohshima H: Ultrastructural changes in odontoblasts and pulp capillaries following cavity preparation in rat molars. Arch Histol Cytol 53(4): 423-438, 1990.
Yoshida S, Chiba J, Ohshima H, Kobayashi S: Microcirculation of oral tissues in the rat fetuses: Scanning electron microscopy of microcorrosion casts (in Japanese). Niigata Dent J 17: 57-63, 1987.
Yoshida S, Ohshima H, Kobayashi S: Ultrastructural changes of terminal pulpal capillaries in the developing molar teeth of rats (in Japanese). Jpn J Oral Biol 30: 807-817, 1988.
Yoshida S, Ohshima H, Kobayashi S: Development of the vascular supply in the dental pulp of rat molars: Scanning electron microscope study of microcorrosion casts. Okajimas Folia Anat Jpn 65(5): 267-282, 1988.
Yoshida S, Ohshima H, Kobayashi S: Vascularization of the enamel organ in developing molar teeth of rats: Scanning electron microscope study of corrosion casts. Okajimas Folia Anat Jpn 66(2-3): 99-112 1989.
Yoshida S, Ohshima H, Sudo H, Kobayashi S: Age changes of terminal pulpal capillaries in rat molar teeth (in Japanese). Jpn J Oral Biol 32: 151-158, 1990.
Ohshima H, Yoshida S, Kobayashi S: Blood vascular architecture of the rat lingual papillae with special reference to their relations to the connective tissue papillae and surface structures: A light and scanning electron microscope study. Acta Anat (Basel) 137(3): 213-221, 1990.
Ohshima H, Yoshida S: The relationship between odontoblasts and pulp capillaries in the process of enamel- and cementum-related dentin formation in rat incisors. Cell Tissue Res 268(1): 51-63, 1992.
Takano Y, Ohshima H: Histochemical demonstration of calcium phosphate depositions in the enamel organ of calcium-loaded tooth germs of the rat.　Arch Comp Biol Tooth Enamel 3: 57-64, 1993.
Takano Y, Sato Y, Ohshima H, Maeda T, Kawahara I, Noguchi I: Histochemical localization and X-ray microanalysis of calcium in the rat submandibular glands: Demonstration of possible sites for microlith induction. Arch Histol Cytol 56(2): 177-184, 1993.
Takano Y, Ohshima H, Maeda T, Sato Y: GBHA staining method: Its application to demonstration of cytoplasmic calcium store in some exocrine and endocrine glands. J Hard Tissue Biol 2(2): 20-27, 1993.
Ohshima H, Kawahara I, Maeda T, Takano Y: The relationship between odontoblasts and immunocompetent cells during dentinogenesis in rat incisors: An immunohistochemical study using OX6-monoclonal antibody. Arch Histol Cytol 57(5): 435-447, 1994.
Ohshima H, Sato O, Kawahara I, Maeda T, Takano Y: Responses of immunocompetent cells to cavity preparation in rat molars: An immunohistochemical study using OX6-monoclonal antibody. Connect Tissue Res 32(1-4): 303-311, 1995.
Nakakura-Ohshima K, Maeda T, Ohshima H, Noda T, Takano Y: Postnatal development of periodontal Ruffini endings in rat incisors: An immunoelectron microscopic study using protein gene product 9.5 (PGP 9.5)-antibody. J Comp Neurol 362(4): 551-564, 1995.
Ohshima H, Maeda T: Kadokeisei to Shizui (Pulpal responses to cavity preparation) (in Japanese). Nihon Shikaishikai Zasshi 48(12): 21-30, 1996.
Takano Y, Hanaizumi Y, Ohshima H: Occurrence of amorphous and crystalline mineral deposits at the epithelial-mesenchymal interface of Ca-loaded rat incisors: An implication of novel calcium binding domains. Anat Rec 245(2): 174-185, 1996.
Yoshida S, Ohshima H: Distribution and organization of peripheral capillaries in the dental pulp and their relationship to odontoblasts. Anat Rec 245(2): 313-326, 1996.
Ohshima H, Takano Y, Sato O, Kawahara I, Maeda T: Responses of class II MHC antigen-expressing cells to cavity preparation. Dentin Pulp Complex: Proceeding of the International Conference on Dentin Pulp Complex 1995, p.316-318, 1996.
Takano Y, Kawahara I, Hoshino M, Takeuchi K, Maeda T, Ohshima H, Hanaizumi Y, Kawano Y: Dendritic Cells: A Novel Cellular Component of the Rat Incisor Enamel Organ in the Late Stages of Enamel Maturation. Adv Dent Res 10(2): 216-224, 1996.
Ohshima H, Maeda T, Takano Y: Acid phosphatase activity in the class II MHC antigen-expressing cells in the rat incisor pulp. Dentistry in Japan 33: 8-14, 1997.
Obinata K, Ohshima H, Takano Y, Ito J: Early ultrastructural changes in the dorsal mucosa of rat tongue after irradiation with special reference to the microvasculature. Radiat Med 15(5): 305-315, 1997.
Ohshima H, Maeda T, Takano Y: Cytochrome oxidase activity in the enamel organ during amelogenesis in rat incisors. Anat Rec 252(4): 519-531, 1998.
Asgor Moral MA, Ohshima H, Maeda T, Hoshino E.: Experimental chronic infection induced in mice by Actinomyces israelii in alginate gel. Arch Oral Biol 43(6): 485-496, 1998.
Kannari N, Ohshima H, Maeda T, Noda T, Takano Y: Class II MHC antigen-expressing cells in the pulp tissue of human deciduous teeth prior to shedding. Arch Histol Cytol 61(1): 1-15, 1998.
Maeda T, Ohshima H: Morphological basis on periodontal Ruffini endings (in Japanese). Kaibogaku Zasshi 73(2): 119-134, 1998.
Hanaizumi Y, Kawano Y, Ohshima H, Hoshino M, Takeuchi K, Maeda T: Three-dimensional direction and interrelationship of prisms in cuspal and cervical enamel of dog tooth. Anat Rec 252(3): 355-368, 1998.
Ohshima H, Maeda T, Takano Y: The distribution and ultrastructure of class II MHC-positive cells in human dental pulp. Cell Tissue Res. 295(1): 151-158, 1999.
Asahito T, Ohshima H, Hanada K, Wakisaka S, Maeda T: Postnatal expression of calretinin immunoreactivity in periodontal Ruffini endings in the rat incisor. A comparison with protein gene product 9.5 (PGP 9.5)-immunoreactivity. Arch Histol Cytol 62(1): 57-69, 1999.
Ohshima H, Wartiovaara J, Thesleff I: Developmental regulation and ultrastructure of glycogen deposits during murine tooth morphogenesis. Cell Tissue Res 297(2): 271-281, 1999.
Nozawa-Inoue K, Ohshima H, Kawano Y, Yamamoto H, Takagi R, Maeda T: Imunocytochemical demonstration of heat shock protein 25 in the rat temporomandibular joint. Arch Histol Cytol 62(5): 483-491, 1999.
Futami T, Fujii N, Ohnishi H, Taguchi N, Kusakari H, Ohshima H, Maeda T: Tissue response to titanium implants in the rat maxilla: ultrastructural and histochemical observations of the bone-titanium interface. J Periodontol 71(2): 288-299, 2000.
Hayashi S, Nakakura-Ohshima K, Ohshima H, Noda T, Honma S, Wakisaka S, Maeda T: The development of terminal Schwann cells associated with periodontal Ruffini endings in the rat incisor ligament. Brain Res 858(1): 167-171, 2000.
Satokata I, Ma L, Ohshima H, Bei M, Woo I, Nishizawa K, Maeda T, Takano Y, Uchiyama M, Heaney S, Peters H, Tang Z, Maxson R, Maas R. : Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet 24(4): 391-395, 2000.
Ohshima H, Ajima H, Kawano Y, Nozawa-Inoue K, Wakisaka S, Maeda T: Transient expression of heat shock protein (Hsp) 25 in the dental pulp and enamel organ during odontogenesis in the rat incisor. Arch Histol Cytol 63(4): 381-395, 2000.
Shimizu A, Nakakura-Ohshima K, Noda T, Maeda T, Ohshima H: Responses of immunocompetent cells in the dental pulp to replantation during the regeneration process in rat molars. Cell Tissue Res 302(2): 221-233, 2000.
Yamamoto H, Hayashi S, Nakakura-Ohshima K, Kawano Y, Nozawa-Inoue K, Ohshima H, Maeda T: Immunocytochemical detection of superoxide dismutases (SODs) in the periodontal Ruffini endings of the rat incisor. Brain Res 905(1-2): 232-235, 2001.
Otsuka Y, Nakakura-Ohshima K, Noda T, Maeda T, Ohshima H: Possible role of heat shock protein (Hsp) 25 in the enamel organ during amelogenesis in the rat molar. Arch Histol Cytol 64(4):369-378, 2001.
Ohshima H, Nakakura-Ohshima K, Yamamoto H, Maeda T: Alteration in the expression of heat shock protein (Hsp) 25-immunoreactivity in the dental pulp of rat molars following tooth replantation. Arch Histol Cytol 64(4):425-437, 2001.
Ohshima H, Nakakura-Ohshima K, Yamamoto H, Maeda T: Responses of odontoblasts to cavity preparation in rat molars as demonstrated by immunocytochemistry for heat shock protein (Hsp) 25. Arch Histol Cytol 64(5):493-501, 2001.
Ohshima H, Nakakura-Ohshima K, Maeda, T: Immunohistochemical study on hard tissue formation in the dental pulp following tooth replantation. Science Report of International Pre-symposium on Biomineralization, p. 15-17, 2001.
Ohshima H, Nakakura-Ohshima K, Maeda T: Expression of heat-shock protein 25 immunoreactivity in the dental pulp and enamel organ during odontogenesis in the rat molar. Connect Tissue Res 43(2-3): 220-223, 2002.
Ohshima H, Maeda T, Maas R, Satokata I: Functional significance of Msx2 gene during tooth development. In: Ishikawa, T., Takahashi, K., Maeda, T., Suda, H., Shimono, M. and Inoue, T. (Eds): Dentin/Pulp Complex, Proceeding of the International Conference on Dentin/Pulp Complex 2001, Quintessence Publishing Co. Ltd., Tokyo, pp. 11-14, 2002.
Ohshima H, Nakakura-Ohshima K: Functional significance of heat shock protein (Hsp) 25 during pulpal regeneration after cavity preparation and tooth replantation in rat molars. Proceeding, Program and Abstract of the 7th International Seminar for JSPS-NRCT Core University Program, pp. 1-5, 2002.
Tamura H, Nakakura-Ohshima K, Maeda T, Ohshima H: Different distribution of immunocompetent cells in the dentogingival junction during root formation in rat molars. J Periodontal Res 38(1): 10-19, 2003.
Ohshima H, Nakakura-Ohshima K, Takeuchi K, Hoshino M, Takano Y, Maeda T: Pulpal regeneration after cavity preparation, with special reference to close spatio-relationships between odontoblasts and immunocompetent cells. Microsc Res Tech 60(5): 483-490, 2003.
Fujii N, Ohnishi H, Shirakura M, Nomura S, Ohshima H, Maeda T: Regeneration of nerve fibers in the peri-implant epithelium incident to implantation in the rat maxilla as demonstrated by immunocytochemistry for protein gene product 9.5 (PGP 9.5) and calcitonin gene-related peptide (CGRP). Clin Oral Implants Res 14(2): 240-247, 2003.
Ohshima H, Kenmotsu S, Harada H: Use of the term apical bud to refer to the apical end of the continuously growing tooth. Arch Comp Biol Tooth Enamel 8: 45-49, 2003.
Shirakura M, Fujii N, Ohnishi H, Taguchi Y, Ohshima H, Nomura S, Maeda T: Tissue response to titanium implantation in the rat maxilla, with special reference to the effects of surface conditions on bone formation. Clin Oral Implants Res 14(6): 687-696, 2003.
Nakakura-Ohshima K, Watanabe J, Kenmotsu S, Ohshima H: Possible role of immunocompetent cells and the expression of heat shock protein (Hsp) 25 in the process of pulpal regeneration after tooth injury in rat molars. J Electron Microsc 52(6): 581-591, 2003.
Ohshima H: Morphogenesis of dentin-pulp complex (in Japanese). Clin Calcium 13(10): 1338-1342, 2003.
Suzuki T, Nomura S, Maeda T, Ohshima H: An immunocytochemical study of pulpal responses to cavity preparation by laser ablation in rat molars using antibodies to heat shock protein (Hsp) 25 and class II MHC antigen. Cell Tissue Res 315(3): 311-319, 2004.
Harada H, Ohshima H: New perspectives on tooth development and dental stem cell niche. Arch Histol Cytol 67(1): 1-11, 2004.
Asawa Y, Aoki K, Ohya K, Ohshima H, Takano Y: Appearance of electron-dense segments: indication of possible conformational changes of pre-mineralizing collagen fibrils in the osteoid of rat bones. J Electron Microsc, 53(4): 423-433, 2004.
Ohshima H: Repair responses of dental pulp to tooth injury and biological properties of dentin-pulp complex (in Japanese). Niigata Dent J, 34(2): 1-13, 2004.
Ohshima H, Nakasone N, Hashimoto E, Sakai H, Nakakura-Ohshima K, Harada H: The eternal tooth germ is formed at the apical end of continuously growing teeth. Arch Oral Biol 50(2): 153-157, 2005.
Ohshima H: Considerable subjects to understand repair responses of dental pulp after tooth injury from a biological point of view (in Japanese). J Jpn Endodont Assoc, 26(2): 103-107, 2005.
Masuyama T, Miyajima K, Ohshima H, Osawa M, Yokoi N, Oikawa T, Taniguchi K: A novel autosomal recessive mutation whitish chalk-like teeth (wct) resembling amelogenesis imperfecta maps to rat chromosome 14 corresponding to human 4q21. Eur J Oral Sci 113(6): 451-456, 2005.
Ohshima H: Cell dynamics in the process of pulpal healing following tooth injuries. J Hard Tissue Biol 14(2): 174-175, 2005.
Suzuki H, Amizuka N, Oda K, Li M, Yoshie H, Ohshima H, Noda M, Maeda T: Histological evidences on altered distribution of osteocytes and bone matrix synthesis in klotho-deficient mice. Arch Histol Cytol 68(5): 371-381, 2005.
Tate Y, Yoshiba K, Yoshiba N, Iwaku M, Okiji T, Ohshima H: Odontoblast responses to GaAlAs laser irradiation in rat molars: an experimental study using heat-shock protein-25-immunohistochemistry. Eur J Oral Sci 114(1): 50-57, 2006.
Nakasone N, Yoshie H, Ohshima H: An immunohistochemical study of the expression of heat-shock protein-25 and cell proliferation in the dental pulp and enamel organ during odontogenesis in rat molars. Arch Oral Biol 51(5): 378-386, 2006.
Kim JY, Cha YG, Cho SW, Kim EJ, Lee MJ, Lee JM, Cai J, Ohshima H, Jung HS: Inhibition of Apoptosis Alters Tooth Shape and Size: Implications for Macrodontia. J Dent Res 85(6): 530-535, 2006.
Kim E, Cho SW, Yang JY, Cai JL, Lee SJ, Ohshima H, Jung HS: Tooth survival and periodontal tissues healing of allo-transplanted teeth in the mice. Oral Diseases 12(4): 395-401, 2006.
Kajiya H, Ito M, Ohshima H, Kenmotsu S, Ries W, Benjamin I, Reddy S: RANK ligand expression in Heat shock factor-2 deficient mouse marrow　stromal/preosteoblast cells. J Cell Biochem 97(6): 1362-1369, 2006.
Tsukamoto-Tanaka H, Ikegame M, Takagi R, Harada H, Ohshima H: Histochemical and immunocytochemical study on hard tissue formation in dental pulp during the healing process after tooth replantation in rat molars. Cell Tissue Res 325(2): 219-229, 2006.
Harada H, Ichimori Y, Yokohama T, Ohshima H, Kawano S, Katsube K, Wakisaka S: Stratum intermedium lineage diverges from ameloblast lineage via Notch signaling. Biochem Biophys Res Commun 340(2): 611-616, 2006.
Yokohama-Tamaki T, Ohshima H, Fujiwara N, Takada Y, Ichimori Y, Wakisaka S, Ohuchi H, Harada H: Cessation of Fgf-10 signaling leads to the transition from crown to root formation due to a defective dental epithelial stem cell compartment. Development 133(7): 1359-1366, 2006.
Nakasone N, Yoshie H, Ohshima H: The relationship between the termination of cell proliferation and expression of heat-shock protein-25 in the rat developing tooth germ. Eur J Oral Sci 114(4): 302-309, 2006.
Kawagishi E, Nakakura-Ohshima K, Nomura S, Ohshima H: Pulpal responses to cavity preparation in aged rat molars. Cell Tissue Res 326(1): 111-122, 2006.
Ogawa R, Saito C, Jung HS, Ohshima H: Capacity of dental pulp differentiation after tooth transplantation. Cell Tissue Res 326(3): 715-724, 2006.
Ohshima H: Repair responses of dental pulp after tooth injury (in Japanese). Clin Res Dent 4(1): 49-57, 2007.
Cho KW, Cho SW, Oh CO, Ryu YK, Ohshima H, Jung HS: The effect of cortical activation on orthodontic tooth movement. Oral Diseases 13(3): 314-319, 2007.
Cho SW, Lee HA, Cai J, Lee MJ, Ohshima H, Jung HS: The primary enamel knot determines the position of the first buccal cusp in developing mice molars. Differentiation 75(5):441-451, 2007.
Hasegawa T, Suzuki H, Yoshie H, Ohshima H: Influence of extended operation time and of occlusal force on determination of pulpal healing pattern in replanted mouse molars. Cell Tissue Res 329(2): 259-272, 2007.
Osawa M, Kenmotsu S, Masuyama T, Taniguchi K, Uchida T, Saito C, Ohshima H: Rat wct mutation prevents differentiation of maturation-stage ameloblasts resulting in hypo-mineralization in incisor teeth. Histochem Cell Biol 128(3): 183-193, 2007.
Osawa M, Kenmotsu S, Masuyama T, Taniguchi K, Uchida T, Saito C, Ohshima H: Rat wct mutation induces a hypo-mineralization form of amelogenesis imperfecta and cyst formation in molar teeth. Cell Tissue Res 330(1): 97-109, 2007.
Harada H, Fujiwara N, Ohshima H: Mechanisms of transitional process from crown to root in tooth development (in Japanese). Dent J Iwate Univ 32(2): 97-104, 2007.
Ohshima H: Biological aspects to understand repair responses of dental pulp (in Japanese). 5th The society for Lesion Sterilization and Tissue Repair Therapy Proceedings, p. 5-13, 2007.
Suzuki H, Amizuka N, Oda K, Noda M, Ohshima H, Maeda T: Involvement of the Klotho Protein in Dentin Formation and Mineralization. Anat Rec (Hoboken) 291(2): 183-190, 2008.
Suzuki H, Amizuka N, Oda K, Noda M, Ohshima H, Maeda T: Histological and elemental analyses of impaired bone mineralization in klotho- deficient mice. J Anat 212(3): 275-285, 2008.
Takamori Y, Suzuki H, Nakakura-Ohshima K, Cai J, Cho SW, Jung HS, Ohshima H: Capacity of dental pulp differentiation in mouse molars as demonstrated by allogenic tooth transplantation. J Histochem Cytochem 56(12): 1075-1086, 2008.
Unno H, Suzuki H, Nakakura-Ohshima K, Jung HS, Ohshima H: Pulpal regeneration following allogenic tooth transplantation into mouse maxilla. Anat Rec (Hoboken) 292(4): 570-579, 2009.
Harada M, Kenmotsu S, Nakasone N, Nakakura-Ohshima K, Ohshima H: Cell dynamics in the pulpal healing process following cavity preparation in rat molars. Histochem Cell Biol 130(4): 773-783, 2008.
Kuratate M, Yoshiba K, Shigetani Y, Yoshiba N, Ohshima H, Okiji T: Immunohistochemical analysis of nestin, osteopontin, and proliferating cells in the reparative process of exposed dental pulp capped with mineral trioxide aggregate. J Endod 34(8): 970-974, 2008.
Cai J, Cho SW, Ishiyama M, Mikami M, Hosoya A, Kozawa Y, Ohshima H, Jung HS: Chick tooth induction revisited. J Exp Zoolog B Mol Dev Evol 312B(5): 465-472, 2009.
Ohshima H: Overview: developmental biology of Hertwig's epithelial root sheath (HERS) and tooth root formation. J Oral Biosci 50(3): 147-153, 2008.
Ali MN, Ejiri S, Kobayashi T, Anwar RB, Oda K, Ohshima H, Saito C: Histologic study of the cellular events during rat mandibular distraction osteogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107(3): 325-335. 2009.
Hashimoto E, Nakakura-Ohshima K, Kenmotsu S, Suzuki H, Nakasone N, Saito C, Harada H, Ohshima H: The relationship between the cusp pattern and plural stem cell compartments in guinea pig cheek teeth by chasing BrdU-labeling. Arch Histol Cytol 71(5): 317-332, 2008.
Ando Y, Honda MJ, Ohshima H, Tonomura A, Ohara T, Itaya T, Kagami H, Ueda M: The induction of dentin bridge-like structures by constructs of subcultured dental pulp-derived cells and porous HA/TCP in porcine teeth. Nagoya J Med Sci 71(1-2): 51-62. 2009.
Cho KW, Cai J, HY, Hosoya A, Ohshima H, Choi KY, Jung HS: ERK signaling regulation in dental epithelial cell via FGF10 signaling. J Exp Zoolog B Mol Dev Evol 312(8): 901-911, 2009.

Publications

(Thesis). Ohshima H: Ultrastructural changes in odontoblasts and pulp capillaries following cavity preparation in rat molars. Arch Histol Cytol 53(4): 423-438, 1990.

Yoshida S, Chiba J, Ohshima H, Kobayashi S: Microcirculation of oral tissues in the rat fetuses: Scanning electron microscopy of microcorrosion casts (in Japanese). Niigata Dent J 17: 57-63, 1987.

Yoshida S, Ohshima H, Kobayashi S: Ultrastructural changes of terminal pulpal capillaries in the developing molar teeth of rats (in Japanese). Jpn J Oral Biol 30: 807-817, 1988.

Yoshida S, Ohshima H, Kobayashi S: Development of the vascular supply in the dental pulp of rat molars: Scanning electron microscope study of microcorrosion casts. Okajimas Folia Anat Jpn 65(5): 267-282, 1988.

Yoshida S, Ohshima H, Kobayashi S: Vascularization of the enamel organ in developing molar teeth of rats: Scanning electron microscope study of corrosion casts. Okajimas Folia Anat Jpn 66(2-3): 99-112 1989.

Yoshida S, Ohshima H, Sudo H, Kobayashi S: Age changes of terminal pulpal capillaries in rat molar teeth (in Japanese). Jpn J Oral Biol 32: 151-158, 1990.

Ohshima H, Yoshida S, Kobayashi S: Blood vascular architecture of the rat lingual papillae with special reference to their relations to the connective tissue papillae and surface structures: A light and scanning electron microscope study. Acta Anat (Basel) 137(3): 213-221, 1990.

Ohshima H, Yoshida S: The relationship between odontoblasts and pulp capillaries in the process of enamel- and cementum-related dentin formation in rat incisors. Cell Tissue Res 268(1): 51-63, 1992.

Takano Y, Ohshima H: Histochemical demonstration of calcium phosphate depositions in the enamel organ of calcium-loaded tooth germs of the rat. Arch Comp Biol Tooth Enamel 3: 57-64, 1993.

Takano Y, Sato Y, Ohshima H, Maeda T, Kawahara I, Noguchi I: Histochemical localization and X-ray microanalysis of calcium in the rat submandibular glands: Demonstration of possible sites for microlith induction. Arch Histol Cytol 56(2): 177-184, 1993.

Takano Y, Ohshima H, Maeda T, Sato Y: GBHA staining method: Its application to demonstration of cytoplasmic calcium store in some exocrine and endocrine glands. J Hard Tissue Biol 2(2): 20-27, 1993.

Ohshima H, Kawahara I, Maeda T, Takano Y: The relationship between odontoblasts and immunocompetent cells during dentinogenesis in rat incisors: An immunohistochemical study using OX6-monoclonal antibody. Arch Histol Cytol 57(5): 435-447, 1994.

Ohshima H, Sato O, Kawahara I, Maeda T, Takano Y: Responses of immunocompetent cells to cavity preparation in rat molars: An immunohistochemical study using OX6-monoclonal antibody. Connect Tissue Res 32(1-4): 303-311, 1995.

Nakakura-Ohshima K, Maeda T, Ohshima H, Noda T, Takano Y: Postnatal development of periodontal Ruffini endings in rat incisors: An immunoelectron microscopic study using protein gene product 9.5 (PGP 9.5)-antibody. J Comp Neurol 362(4): 551-564, 1995.

Ohshima H, Maeda T: Kadokeisei to Shizui (Pulpal responses to cavity preparation) (in Japanese). Nihon Shikaishikai Zasshi 48(12): 21-30, 1996.

Takano Y, Hanaizumi Y, Ohshima H: Occurrence of amorphous and crystalline mineral deposits at the epithelial-mesenchymal interface of Ca-loaded rat incisors: An implication of novel calcium binding domains. Anat Rec 245(2): 174-185, 1996.

Yoshida S, Ohshima H: Distribution and organization of peripheral capillaries in the dental pulp and their relationship to odontoblasts. Anat Rec 245(2): 313-326, 1996.

Ohshima H, Takano Y, Sato O, Kawahara I, Maeda T: Responses of class II MHC antigen-expressing cells to cavity preparation. Dentin Pulp Complex: Proceeding of the International Conference on Dentin Pulp Complex 1995, p.316-318, 1996.

Takano Y, Kawahara I, Hoshino M, Takeuchi K, Maeda T, Ohshima H, Hanaizumi Y, Kawano Y: Dendritic Cells: A Novel Cellular Component of the Rat Incisor Enamel Organ in the Late Stages of Enamel Maturation. Adv Dent Res 10(2): 216-224, 1996.

Ohshima H, Maeda T, Takano Y: Acid phosphatase activity in the class II MHC antigen-expressing cells in the rat incisor pulp. Dentistry in Japan 33: 8-14, 1997.

Obinata K, Ohshima H, Takano Y, Ito J: Early ultrastructural changes in the dorsal mucosa of rat tongue after irradiation with special reference to the microvasculature. Radiat Med 15(5): 305-315, 1997.

Ohshima H, Maeda T, Takano Y: Cytochrome oxidase activity in the enamel organ during amelogenesis in rat incisors. Anat Rec 252(4): 519-531, 1998.

Asgor Moral MA, Ohshima H, Maeda T, Hoshino E.: Experimental chronic infection induced in mice by Actinomyces israelii in alginate gel. Arch Oral Biol 43(6): 485-496, 1998.

Kannari N, Ohshima H, Maeda T, Noda T, Takano Y: Class II MHC antigen-expressing cells in the pulp tissue of human deciduous teeth prior to shedding. Arch Histol Cytol 61(1): 1-15, 1998.

Maeda T, Ohshima H: Morphological basis on periodontal Ruffini endings (in Japanese). Kaibogaku Zasshi 73(2): 119-134, 1998.

Hanaizumi Y, Kawano Y, Ohshima H, Hoshino M, Takeuchi K, Maeda T: Three-dimensional direction and interrelationship of prisms in cuspal and cervical enamel of dog tooth. Anat Rec 252(3): 355-368, 1998.

Ohshima H, Maeda T, Takano Y: The distribution and ultrastructure of class II MHC-positive cells in human dental pulp. Cell Tissue Res. 295(1): 151-158, 1999.

Asahito T, Ohshima H, Hanada K, Wakisaka S, Maeda T: Postnatal expression of calretinin immunoreactivity in periodontal Ruffini endings in the rat incisor. A comparison with protein gene product 9.5 (PGP 9.5)-immunoreactivity. Arch Histol Cytol 62(1): 57-69, 1999.

Ohshima H, Wartiovaara J, Thesleff I: Developmental regulation and ultrastructure of glycogen deposits during murine tooth morphogenesis. Cell Tissue Res 297(2): 271-281, 1999.

Nozawa-Inoue K, Ohshima H, Kawano Y, Yamamoto H, Takagi R, Maeda T: Imunocytochemical demonstration of heat shock protein 25 in the rat temporomandibular joint. Arch Histol Cytol 62(5): 483-491, 1999.

Futami T, Fujii N, Ohnishi H, Taguchi N, Kusakari H, Ohshima H, Maeda T: Tissue response to titanium implants in the rat maxilla: ultrastructural and histochemical observations of the bone-titanium interface. J Periodontol 71(2): 288-299, 2000.

Hayashi S, Nakakura-Ohshima K, Ohshima H, Noda T, Honma S, Wakisaka S, Maeda T: The development of terminal Schwann cells associated with periodontal Ruffini endings in the rat incisor ligament. Brain Res 858(1): 167-171, 2000.

Satokata I, Ma L, Ohshima H, Bei M, Woo I, Nishizawa K, Maeda T, Takano Y, Uchiyama M, Heaney S, Peters H, Tang Z, Maxson R, Maas R. : Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet 24(4): 391-395, 2000.

Ohshima H, Ajima H, Kawano Y, Nozawa-Inoue K, Wakisaka S, Maeda T: Transient expression of heat shock protein (Hsp) 25 in the dental pulp and enamel organ during odontogenesis in the rat incisor. Arch Histol Cytol 63(4): 381-395, 2000.

Shimizu A, Nakakura-Ohshima K, Noda T, Maeda T, Ohshima H: Responses of immunocompetent cells in the dental pulp to replantation during the regeneration process in rat molars. Cell Tissue Res 302(2): 221-233, 2000.

Yamamoto H, Hayashi S, Nakakura-Ohshima K, Kawano Y, Nozawa-Inoue K, Ohshima H, Maeda T: Immunocytochemical detection of superoxide dismutases (SODs) in the periodontal Ruffini endings of the rat incisor. Brain Res 905(1-2): 232-235, 2001.

Otsuka Y, Nakakura-Ohshima K, Noda T, Maeda T, Ohshima H: Possible role of heat shock protein (Hsp) 25 in the enamel organ during amelogenesis in the rat molar. Arch Histol Cytol 64(4):369-378, 2001.

Ohshima H, Nakakura-Ohshima K, Yamamoto H, Maeda T: Alteration in the expression of heat shock protein (Hsp) 25-immunoreactivity in the dental pulp of rat molars following tooth replantation. Arch Histol Cytol 64(4):425-437, 2001.

Ohshima H, Nakakura-Ohshima K, Yamamoto H, Maeda T: Responses of odontoblasts to cavity preparation in rat molars as demonstrated by immunocytochemistry for heat shock protein (Hsp) 25. Arch Histol Cytol 64(5):493-501, 2001.

Ohshima H, Nakakura-Ohshima K, Maeda T: Expression of heat-shock protein 25 immunoreactivity in the dental pulp and enamel organ during odontogenesis in the rat molar. Connect Tissue Res 43(2-3): 220-223, 2002.

Ohshima H, Nakakura-Ohshima K: Functional significance of heat shock protein (Hsp) 25 during pulpal regeneration after cavity preparation and tooth replantation in rat molars. Proceeding, Program and Abstract of the 7th International Seminar for JSPS-NRCT Core University Program, pp. 1-5, 2002.

Tamura H, Nakakura-Ohshima K, Maeda T, Ohshima H: Different distribution of immunocompetent cells in the dentogingival junction during root formation in rat molars. J Periodontal Res 38(1): 10-19, 2003.

Ohshima H, Nakakura-Ohshima K, Takeuchi K, Hoshino M, Takano Y, Maeda T: Pulpal regeneration after cavity preparation, with special reference to close spatio-relationships between odontoblasts and immunocompetent cells. Microsc Res Tech 60(5): 483-490, 2003.

Ohshima H, Kenmotsu S, Harada H: Use of the term apical bud to refer to the apical end of the continuously growing tooth. Arch Comp Biol Tooth Enamel 8: 45-49, 2003.

Shirakura M, Fujii N, Ohnishi H, Taguchi Y, Ohshima H, Nomura S, Maeda T: Tissue response to titanium implantation in the rat maxilla, with special reference to the effects of surface conditions on bone formation. Clin Oral Implants Res 14(6): 687-696, 2003.

Nakakura-Ohshima K, Watanabe J, Kenmotsu S, Ohshima H: Possible role of immunocompetent cells and the expression of heat shock protein (Hsp) 25 in the process of pulpal regeneration after tooth injury in rat molars. J Electron Microsc 52(6): 581-591, 2003.

Ohshima H: Morphogenesis of dentin-pulp complex (in Japanese). Clin Calcium 13(10): 1338-1342, 2003.

Suzuki T, Nomura S, Maeda T, Ohshima H: An immunocytochemical study of pulpal responses to cavity preparation by laser ablation in rat molars using antibodies to heat shock protein (Hsp) 25 and class II MHC antigen. Cell Tissue Res 315(3): 311-319, 2004.

Harada H, Ohshima H: New perspectives on tooth development and dental stem cell niche. Arch Histol Cytol 67(1): 1-11, 2004.

Asawa Y, Aoki K, Ohya K, Ohshima H, Takano Y: Appearance of electron-dense segments: indication of possible conformational changes of pre-mineralizing collagen fibrils in the osteoid of rat bones. J Electron Microsc, 53(4): 423-433, 2004.

Ohshima H: Repair responses of dental pulp to tooth injury and biological properties of dentin-pulp complex (in Japanese). Niigata Dent J, 34(2): 1-13, 2004.

Ohshima H, Nakasone N, Hashimoto E, Sakai H, Nakakura-Ohshima K, Harada H: The eternal tooth germ is formed at the apical end of continuously growing teeth. Arch Oral Biol 50(2): 153-157, 2005.

Ohshima H: Considerable subjects to understand repair responses of dental pulp after tooth injury from a biological point of view (in Japanese). J Jpn Endodont Assoc, 26(2): 103-107, 2005.

Masuyama T, Miyajima K, Ohshima H, Osawa M, Yokoi N, Oikawa T, Taniguchi K: A novel autosomal recessive mutation whitish chalk-like teeth (wct) resembling amelogenesis imperfecta maps to rat chromosome 14 corresponding to human 4q21. Eur J Oral Sci 113(6): 451-456, 2005.

Tate Y, Yoshiba K, Yoshiba N, Iwaku M, Okiji T, Ohshima H: Odontoblast responses to GaAlAs laser irradiation in rat molars: an experimental study using heat-shock protein-25-immunohistochemistry. Eur J Oral Sci 114(1): 50-57, 2006.

Nakasone N, Yoshie H, Ohshima H: An immunohistochemical study of the expression of heat-shock protein-25 and cell proliferation in the dental pulp and enamel organ during odontogenesis in rat molars. Arch Oral Biol 51(5): 378-386, 2006.

Kim JY, Cha YG, Cho SW, Kim EJ, Lee MJ, Lee JM, Cai J, Ohshima H, Jung HS: Inhibition of Apoptosis Alters Tooth Shape and Size: Implications for Macrodontia. J Dent Res 85(6): 530-535, 2006.

Kim E, Cho SW, Yang JY, Cai JL, Lee SJ, Ohshima H, Jung HS: Tooth survival and periodontal tissues healing of allo-transplanted teeth in the mice. Oral Diseases 12(4): 395-401, 2006.

Kajiya H, Ito M, Ohshima H, Kenmotsu S, Ries W, Benjamin I, Reddy S: RANK ligand expression in Heat shock factor-2 deficient mouse marrow stromal/preosteoblast cells. J Cell Biochem 97(6): 1362-1369, 2006.

Harada H, Ichimori Y, Yokohama T, Ohshima H, Kawano S, Katsube K, Wakisaka S: Stratum intermedium lineage diverges from ameloblast lineage via Notch signaling. Biochem Biophys Res Commun 340(2): 611-616, 2006.

Home Page of Hayato Ohshima

Takano Y, Ohshima H: Histochemical demonstration of calcium phosphate depositions in the enamel organ of calcium-loaded tooth germs of the rat.　Arch Comp Biol Tooth Enamel 3: 57-64, 1993.

Kajiya H, Ito M, Ohshima H, Kenmotsu S, Ries W, Benjamin I, Reddy S: RANK ligand expression in Heat shock factor-2 deficient mouse marrow　stromal/preosteoblast cells. J Cell Biochem 97(6): 1362-1369, 2006.