Clinico-statistical study on autologous blood transfusion
- Effect of recombinant human erythropoietin (EPO) and iron preparations -


Masataka Kaji,1) Yasushi Ohashi,1) Yuuichi Muto, 1) Ritsuo Takagi,1) Yukio Hattori,1), Jyunichi Fukuda, 1) Genji Someya2)
1)Second Department of Oral and Maxillofacial surgery, School of Dentistry, Niigata University
(Chief: Prof. Yasushi Ohashi)
2)Department of Dental Anesthesia, Niigata University Dental Hospital
(Chief: Prof. Genji Someya)


Abstract:
@Two hundred and ninety-one operative cases, who received autologous blood transfusions in our department from June 1988 to December 1996, were studied clinico-statistically. There were 274 cases of jaw deformities, 8 cases of malignant tumors and 5 cases of benign tumors. Autologous blood transfusion increased year by year, and consequently the rate of autologous blood transfusion among blood transfusions was above 90% after 1995. Recently homologoud blood transfusion have not been required except for malignant tumors.
@The effects of recombinant human erythropoietin (EPO) and iron preparations (Fe) were investigated. the results were as follows: In the EPO and Fe group, just after sutologous blood collection of 800 ml the mean values for Hb and Ht were 0.90 and 0.90 of the baseline values before autologous blood collection, respectively. And in 4 to 14 days after surgery the mean values were 0.96 and 0.96, respectively. In the EPO and Fe group, Hb and Ht recovered after surgery more quickly than in the control group.


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