ResearchEnglish

■ Dental implant-related research
The survival rate of dental implants is over 90%, even after ten years of treatment.
Although the dental implant is a reliable procedure, it is not uncommon to encounter clinical problems.
In order to provide a safer and more secure implant treatment to patients, we are engaged in several research projects that may answer common clinical questions.
1. Bone and forces
Effects of tightening torque and dynamic loading of the implant abutment screw on the marginal bone.
Effect of the torque value on the abutment screw morphology.
Animal experiment model for the study of the osseointegration collapse mechanism.
Histological changes of ovariectomized rat peri-implant bone under mechanical loading.
2. Implant and bone quality
Research for the optimal conditions for autologous bone grafting focusing on bone cell network reconstruction
 and bone quality of transplanted bone
Effect of the collagen cross-link quality on implant osseointegration in rats.
Histological study of the effect of bone quality on transplanted bone and transplant site.
Effect of Collagen Cross-Link Deficiency on Incorporation of Grafted Bone。
3. Implant surface characteristics and peri-implant cells
Histological observation of bone marrow cell migration after dental implant placement and bone grafting in GFP rats
Interaction between the implant surface characteristics and peri-implant cells at the initial stage of osseointegration.
Topography Influences Adherent Cell Regulation of Osteoclastogenesis
4. Clinical research
Implant treatment for patients with cemento-osseous dysplasia at Niigata University Medical and Dental Hospital
■ Periodontal ligament-related research
Between the tooth root and bone surfaces, there is a cushion-like tissue called a “periodontal ligament.”
It is a specialized fibrous tissue and plays an important role in the maintenance and restoration of teeth.
However, due to its complex structure, there are many biological processes that we still do not understand; hence, we are conducting basic and clinical research to elucidate its biological mechanisms.
Elucidation of the background that causes individual differences in the response of the periodontal ligament to
 occlusal force
Regeneration of periodontal ligament in natural teeth.
Development of next-generation implants with the periodontal ligament.
■ Dental metal allergies-related research
Currently, there is little knowledge regarding dental metal allergies.
Our department is collecting clinical data and conducting basic research at the cellular level.
Research on metal allergies and psoriasis
Research on metal allergies and atopic dermatitis
Clinical study on dental metal allergies
■ Dental materials and devices-related research
We are engaged in the research of dental materials, as well as in the development and evaluation of dental equipment under the motto “Equipment goes through dentistry”.
Development of SiC fiber reinforced dental polymer materials and face guard materials.
Metallization of zirconia surfaces by titanium sputtering.
Research and evaluation of tooth preparation methods more suitable for CAD/CAM crowns.
■ Root fractures-related research
In Japan and western countries, tooth loss due to caries and periodontal disease is decreasing year by year, while loss due to "tooth fracture" is increasing. Since Japan is a country with a super-aging society, the number of long-term prosthetic cases is constantly increasing; consequently, there will be a need for new treatments and solutions for root fractures in the future.
Clinical studies on root fracture restoration treatment
Development of periodontal ligament regeneration method for root fractured teeth
■ Dental education-related research
Learning at the Faculty of Dentistry is the first step in lifelong learning for dentists. It is no exaggeration to say that education in the Faculty of Dentistry supports the dental community.
In order to provide better education, we are conducting research on the differences in learning effects depending on the learning method.
Evaluation of the effect of the learning method on the student`s treatment planning ability.
Research on the reliability of evaluations using rubrics in the “comprehensive oral rehabilitation training practice.
Research on the dental student’s self-assessment ability of single crown preparation in a class of fixed
 partial dentures.
Development of dental clinical skill evaluation method at the time of graduation using an integrated disease model
■ Other basic and clinical research
Development of bone augmentation method using antioxidants.
Development of bone augmentation method by epigenetic control.
Development of bone regeneration methods that can enhance bone formation.
Development of zirconia drills that can promote osseointegration.